Fallout 4 has a handful of challenging enemies around the Commonwealth, but one terrifying cut creature with an interesting backstory would’ve raised the bar. Fallout 4 was the first game in the franchise to move to a more modern combat system, and while that made it more engaging, it also raised the difficulty. Without proper preparation, some of the strongest enemies, like Mirelurk Queens or Deathclaws can be long and frustrating encounters. Regardless, these larger fights are some of the most memorable events throughout the game.