There are many ways to stay alive while on a crusade in Cult of the Lamb, from better weapons, better Tarot Cards, and a multitude of different hearts to protect you from the evil within. The Diseased Heart is one such means of survival.

There are three different types of hearts in Cult of the Lamb, ranging from the standard Red Heart that represents basic health, to a temporary Blue Heart that can boost your health for one specific crusade. A Diseased Heart, on the other hand, is one of the more useful pick-ups as you continue your journey, since it can mean the different between life and death.